Hiroki Tanaka Selected Research

Boron Neutron Capture Therapy

5/2022	Boron neutron capture therapy and add-on bevacizumab in patients with recurrent malignant glioma.
4/2022	Compassionate Treatment of Brainstem Tumors with Boron Neutron Capture Therapy: A Case Series.
1/2022	Boron neutron capture therapy using dodecaborated albumin conjugates with maleimide is effective in a rat glioma model.
12/2021	Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system.
12/2021	Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation.
11/2021	Suppression of Tumor Growth in a Rabbit Hepatic Cancer Model by Boron Neutron Capture Therapy With Liposomal Boron Delivery Systems.
4/2021	Salvage Boron Neutron Capture Therapy for Malignant Brain Tumor Patients in Compliance with Emergency and Compassionate Use: Evaluation of 34 Cases in Taiwan.
1/2021	Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study.
1/2021	HIF-1α affects sensitivity of murine squamous cell carcinoma to boron neutron capture therapy with BPA.
1/2021	Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial.

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Hiroki Tanaka Research Topics

Disease

86	Neoplasms (Cancer) 09/2022 - 04/2006
19	Neoplasm Metastasis (Metastasis) 08/2021 - 11/2005
16	Inflammation (Inflammations) 01/2022 - 01/2017
15	Hypoxia (Hypoxemia) 01/2022 - 12/2006
11	Abdominal Aortic Aneurysm 07/2022 - 01/2009
11	Melanoma (Melanoma, Malignant) 07/2022 - 07/2006
11	Carcinoma (Carcinomatosis) 12/2021 - 04/2006
10	Glioma (Gliomas) 05/2022 - 05/2009
8	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 07/2009
8	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 12/2006
8	Aneurysm (Aneurysms) 01/2021 - 04/2013
7	Brain Neoplasms (Brain Tumor) 01/2022 - 03/2015
7	Colitis 01/2021 - 07/2009
6	Infections 04/2020 - 01/2016
6	Stomach Neoplasms (Stomach Cancer) 01/2020 - 06/2014
6	Hyperthermia 12/2019 - 01/2012
5	Fibrosis (Cirrhosis) 01/2021 - 01/2017
5	Crohn Disease (Crohn's Disease) 12/2020 - 03/2012
5	Pathologic Constriction (Stenosis) 06/2020 - 06/2011
5	Rupture 01/2020 - 01/2015
4	Poisoning 09/2022 - 01/2017
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 11/2014
4	Hypothermia 01/2022 - 10/2019
4	Non-alcoholic Fatty Liver Disease 01/2021 - 08/2014
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 01/2008
4	Varicose Veins (Varicose Vein) 08/2019 - 11/2009
4	Colonic Neoplasms (Colon Cancer) 06/2018 - 01/2009
4	Iron Overload 03/2017 - 11/2011
3	Necrosis 05/2022 - 01/2010
3	Glioblastoma (Glioblastoma Multiforme) 05/2022 - 01/2019
3	Wounds and Injuries (Trauma) 11/2021 - 01/2011
3	Liver Neoplasms (Liver Cancer) 11/2021 - 06/2014
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 11/2015
3	Ulcerative Colitis 11/2020 - 05/2008
3	Breast Neoplasms (Breast Cancer) 11/2020 - 01/2013
3	Fever (Fevers) 06/2020 - 06/2004
3	Body Weight (Weight, Body) 09/2019 - 05/2008
2	Septic Shock (Toxic Shock Syndrome) 09/2022 - 01/2020
2	Disease Progression 05/2022 - 07/2020
2	Hypertrophy 02/2022 - 01/2016
2	Thrombosis (Thrombus) 01/2022 - 01/2013

Drug/Important Bio-Agent (IBA)

17	Bromodeoxyuridine (BrdU)IBA 12/2019 - 01/2008
16	BoronIBA 09/2022 - 03/2013
13	LipidsIBA 11/2021 - 05/2012
13	Proteins (Proteins, Gene)FDA Link 08/2021 - 04/2012
9	Messenger RNA (mRNA)IBA 06/2021 - 04/2012
9	CytokinesIBA 01/2021 - 02/2011
9	IronIBA 06/2017 - 03/2011
7	Therapeutic UsesIBA 12/2020 - 07/2009
7	SodiumIBA 12/2019 - 07/2009
6	pimonidazoleIBA 01/2022 - 10/2010
6	RNA (Ribonucleic Acid)IBA 04/2020 - 09/2015
6	Niacinamide (Nicotinamide)FDA LinkGeneric 12/2019 - 01/2009
5	Biological ProductsIBA 01/2022 - 05/2012
5	Dextran SulfateIBA 01/2021 - 02/2011
5	Adalimumab (Humira)FDA Link 01/2021 - 03/2012
5	Pancreatic Elastase (Elastase)IBA 01/2021 - 04/2013
4	Bevacizumab (Avastin)FDA Link 05/2022 - 03/2013
4	HMGB1 Protein (HMG1)IBA 01/2022 - 10/2020
4	FerrichromeIBA 01/2021 - 10/2016
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2014
4	Boron-10IBA 01/2020 - 11/2009
4	Infliximab (Remicade)FDA Link 12/2017 - 05/2008
4	Oxygen (Dioxygen)IBA 01/2016 - 12/2006
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022 - 12/2017
3	AntigensIBA 07/2022 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 03/2022 - 10/2019
3	Indicators and Reagents (Reagents)IBA 02/2022 - 09/2015
3	Phenylalanine (L-Phenylalanine)FDA Link 12/2021 - 12/2015
3	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2010
3	EmulsionsIBA 09/2020 - 06/2014
3	Anti-Bacterial Agents (Antibiotics)IBA 06/2020 - 01/2016
3	Apolipoproteins E (ApoE)IBA 01/2020 - 01/2017
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2016
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 07/2006
3	4-boronophenylalanineIBA 12/2019 - 03/2013
3	Tirapazamine (SR 4233)IBA 12/2019 - 01/2012
3	Phenobarbital (Luminal)FDA Link 01/2018 - 01/2010
3	HepcidinsIBA 03/2017 - 02/2014
3	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2017 - 02/2016
3	CarbonIBA 08/2015 - 01/2008
2	Colchicine FDA LinkGeneric 09/2022 - 01/2020
2	EndotoxinsIBA 09/2022 - 01/2020
2	Eicosapentaenoic AcidIBA 07/2022 - 01/2022
2	AlbuminsIBA 01/2022 - 01/2017
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 02/2011

Therapy/Procedure

35	Boron Neutron Capture Therapy 05/2022 - 07/2009
26	Therapeutics 05/2022 - 06/2004
13	Drug Therapy (Chemotherapy) 04/2022 - 06/2014
10	Radiotherapy 04/2022 - 01/2009
4	Intra-Arterial Injections 11/2021 - 06/2014
4	Neutron Capture Therapy 10/2018 - 04/2016
4	Gastrectomy 10/2015 - 01/2014
3	Rewarming 01/2022 - 10/2019
3	Transplantation 01/2021 - 07/2009
3	Aftercare (After-Treatment) 06/2020 - 12/2006
3	Lasers (Laser) 02/2016 - 01/2013
3	Pancreaticoduodenectomy 10/2015 - 11/2014
3	Renal Dialysis (Hemodialysis) 10/2015 - 06/2004
2	Re-Irradiation 05/2022 - 01/2021